Perceptive Advisors Adjusts Lyra Therapeutics Stake

TL;DR

Perceptive Advisors filed an amendment on Lyra Therapeutics (LYRA) - ownership change.

AI Summary

Perceptive Advisors LLC, along with affiliated entities Perceptive Life Sciences Master Fund, Ltd. and Perceptive LS (A), LLC, has amended their Schedule 13D filing regarding Lyra Therapeutics, Inc. as of August 15, 2024. The filing indicates a change in beneficial ownership, though specific share counts or dollar amounts are not detailed in this excerpt.

Why It Matters

This filing signals a potential shift in significant ownership of Lyra Therapeutics, which could influence the company's strategic direction or stock performance.

Risk Assessment

Risk Level: medium — Changes in beneficial ownership by significant holders can indicate evolving investment strategies or potential activism, impacting stock volatility.

Key Players & Entities

• Lyra Therapeutics, Inc. (company) — Subject Company
• Perceptive Advisors LLC (company) — Filing Entity
• Perceptive Life Sciences Master Fund, Ltd. (company) — Group Member
• Perceptive LS (A), LLC (company) — Group Member
• Joseph Edelman (person) — Group Member

FAQ

Key Financial Figures

• $0.001 — Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securiti

Filing Documents

• d880174dsc13da.htm (SC 13D/A) — 79KB
• 0001193125-24-201452.txt ( ) — 80KB

of the Schedule 13D is amended and restated as followed

Item 2 of the Schedule 13D is amended and restated as followed: (a) This Amendment No. 4 to the Schedule 13D is being filed by Perceptive Advisors LLC ( Perceptive Advisors or Perceptive ), Joseph Edelman ( Mr. Edelman ), Perceptive Life Sciences Master Fund, Ltd. (the Master Fund ), and Perceptive LS (A), LLC ( Perceptive LS , and together with Perceptive Advisors, Mr. Edelman, and the Master Fund, each of the foregoing, a Reporting Person , and collectively, the Reporting Persons ). Perceptive LS GP, LLC ( GP ) is the manager of Perceptive LS. Perceptive Advisors serves as the investment advisor to the Master Fund, and Mr. Edelman is the managing member of Perceptive Advisors and the sole managing member of GP. The agreement among the Reporting Persons to file this Schedule 13D jointly in accordance with Rule 13d-1(k) of the Securities Exchange Act of 1934, as amended, is attached as Exhibit 1 to the initial Schedule 13D filed June 1, 2020. (b) The address of the principal business office of each of the Reporting Persons is 51 Astor Place 10th Floor, New York, NY 10003. (c) The principal business of Perceptive Advisors is managing funds in connection with purchasing, holding and selling securities for investment purposes. The principal business of the Master Fund and Perceptive LS is to invest in securities. The principal occupation of Mr. Edelman is as the managing member of Perceptive Advisors and other related entities. (d) During the last five years, none of the Reporting Persons, nor to the Reporting Persons knowledge, any of the persons listed on Schedule A to this Amendment No. 4 to Schedule 13D, has been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors). (e) During the last five years, none of the Reporting Persons, nor to the Reporting Persons knowledge, any of the persons listed in Schedule A, has been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a re

of the Schedule 13D is amended and supplemented as follows

Item 5 of the Schedule 13D is amended and supplemented as follows: (a) The information set forth in rows 11 and 13 of the cover pages to this Schedule 13D is incorporated by reference. The percentage set forth in row 13 is based on 65,456,735 outstanding shares of Common Stock as of August 1, 2024 as reported by the Issuer in its Form 10-Q filed with the Securities and Exchange Commission on August 14, 2024. (b) The information set forth in rows 7 through 10 of the cover pages to this Schedule 13D is incorporated by reference.

SIGNATURES

SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Dated: August 15, 2024 PERCEPTIVE ADVISORS LLC By: /s/ Joseph Edelman Name: Joseph Edelman Title: Managing Member /s/ Joseph Edelman JOSEPH EDELMAN PERCEPTIVE LIFE SCIENCES MASTER FUND, LTD. By: Perceptive Advisors LLC By: /s/ Joseph Edelman Name: Joseph Edelman Title: Managing Member PERCEPTIVE LS (A), LLC By: Perceptive LS GP, LLC By: /s/ Joseph Edelman Name: Joseph Edelman Title: Member Schedule A The following sets forth the name, address, principal occupation, citizenship and beneficial ownership of Ordinary Shares (to the extent not pursuant to Item 5(a)) of each director of the Master Fund (to the extent not set forth in Item 2). Master Fund Name and Citizenship Position Principal Business Address Beneficial Ownership of Ordinary Shares Scott Dakers (United Kingdom) Director c/o Elian Fiduciary Services (Cayman) Limited 190 Elgin Avenue, George Town Grand Cayman KY1-9007 Cayman Islands None Ernest A. Morrison (United Kingdom) Director Cox Hallett Wilkinson Milner House 18 Parliament Street P.O. Box HM 1561 Hamilton HM FX Bermuda None James Nicholas (United States) Director c/o GenesisPoint LLC 30 Old Kings Highway S Darien, CT 06820 None

View Full Filing

View this SC 13D/A filing on SEC EDGAR