NEONC TECHNOLOGIES HOLDINGS, INC. Files 8-K for Material Agreement

Ticker: NTHI · Form: 8-K · Filed: Oct 9, 2025 · CIK: 1979414

Sentiment: neutral

Topics: material-agreement, 8-k

TL;DR

NEONC TECHNOLOGIES HOLDINGS, INC. signed a big deal on Oct 4th. 8-K filed.

AI Summary

On October 4, 2025, NEONC TECHNOLOGIES HOLDINGS, INC. entered into a material definitive agreement. The company, incorporated in Delaware with its principal executive offices in Calabasas, CA, filed this 8-K report on October 9, 2025, detailing this significant event.

Why It Matters

This filing indicates a significant development for NEONC TECHNOLOGIES HOLDINGS, INC., potentially impacting its business operations, financial standing, or strategic direction.

Risk Assessment

Risk Level: medium — Entering into a material definitive agreement can introduce new risks or opportunities that are not yet fully understood by the market.

Key Numbers

Key Players & Entities

FAQ

What type of material definitive agreement did NEONC TECHNOLOGIES HOLDINGS, INC. enter into?

The filing indicates an 'Entry into a Material Definitive Agreement' as an item of disclosure, but the specific details of the agreement are not provided in this excerpt.

What is the primary business of NEONC TECHNOLOGIES HOLDINGS, INC.?

NEONC TECHNOLOGIES HOLDINGS, INC. is classified under the Standard Industrial Classification code 2834, which pertains to Pharmaceutical Preparations.

When was the earliest event reported in this 8-K filing?

The earliest event reported was on October 4, 2025.

What is the company's principal executive office address?

The company's principal executive offices are located at 23975 Park Sorrento, Suite 205, Calabasas, CA 91302.

What is the fiscal year end for NEONC TECHNOLOGIES HOLDINGS, INC.?

The company's fiscal year ends on December 31.

Filing Stats: 894 words · 4 min read · ~3 pages · Grade level 12.1 · Accepted 2025-10-09 09:16:12

Key Financial Figures

Filing Documents

01

Item 1.01. Entry into a Material Definitive Agreement On October 4, 2025, NeOnc Technologies Holdings, Inc. (the "Company") entered into a Master Services Agreement (the "MSA") with Insights Pharmaceutical Research LLC ("IROS"), a contract research organization based in the United Arab Emirates and an affiliate of Group 42 Holding Ltd. and Mubadala Investment Company PJSC. The MSA establishes the terms and conditions under which IROS will provide clinical research services to in support of the Company's clinical development programs in the UAE. The MSA will be transferred to the Company's controlled UAE subsidiary (NuroCure) once its incorporation is complete. Under the MSA, IROS will serve as the Company's contract research organization for clinical trials conducted in the UAE and will be responsible for regulatory submissions, site selection and management, clinical monitoring, data management, and trial reporting activities, in accordance with Good Clinical Practice guidelines and applicable UAE and FDA regulations. Each specific project or study will be governed by a separate work order under the MSA. The first work order to be executed under the MSA covers a multi-site, randomized Phase 2b/3 study titled A Multi-Site, Randomized, Phase 2b/3 Study Evaluating Overall Survival of Intranasal NEO100 in Patients with Progressive or Recurrent Grade III Astrocytomas and Glioblastoma Multiforme (GBM), Stratified by IDH1 Mutation Status, Compared to Best Standard of Care. The initial work order has an estimated budget of approximately $2.4 million in service fees and $0.1 million in pass-through costs, payable in four milestone-based installments through study completion. The Company retains all rights to clinical data, intellectual property, and regulatory filings arising from the studies performed under the MSA. The MSA sets out the general terms on which all projects will be conducted. In addition to performance commitments and payment terms, it includes customa

01

Item 7.01. Regulation FD Disclosure. On October 9, 2025, the Company issued a press release announcing two major strategic developments that solidify its expansion into the Middle East. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K. The information in this Item 7.01 and Exhibit 99.1 furnished hereto shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing.

Financial Statements and Exhibits

Financial Statements and Exhibits. (d) Exhibits Exhibit No. Description 10.1 Master Services Agreement, dated October 4, 2025 99.1 Press Release, dated October 9, 2025 104 Cover Page Interactive Data File (embedded within the Inline XBRL document) 1

SIGNATURES

SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Dated: October 9, 2025 NeOnc Technologies Holdings, Inc. By: /s/ Amir Heshmatpour Name: Amir Heshmatpour Title: President and Executive Chairman 2

View Full Filing

View this 8-K filing on SEC EDGAR

View on Read The Filing