Spruce Biosciences, Inc. (SPRB) — SEC Filings

Spruce Biosciences, Inc. (SPRB) — 44 SEC filings. Latest: 8-K (Dec 15, 2025). Includes 19 8-K, 8 SC 13G/A, 5 10-Q.

View Spruce Biosciences, Inc. on SEC EDGAR

Overview

Spruce Biosciences, Inc. (SPRB) is a publicly traded company tracked on ReadTheFiling. The most recent enriched filing is a 8-K filed on Dec 15, 2025: Spruce Biosciences, Inc. announced on December 11, 2025, a change in its principal executive offices to 611 Gateway Boulevard, Suite 740, South San Francisco, California. This filing also indicates potential changes related to directors, officers, and compensatory arrangements, though specific detai

Sentiment Summary

Across 44 filings, the sentiment breakdown is: 1 bullish, 6 bearish, 37 neutral. The dominant filing sentiment for Spruce Biosciences, Inc. is neutral.

Filing Type Overview

Spruce Biosciences, Inc. (SPRB) has filed 19 8-K, 5 10-Q, 1 DEFA14A, 2 DEF 14A, 2 10-K, 8 SC 13G/A, 5 SC 13D/A, 2 SC 13G with the SEC between Jan 2024 to Dec 2025.

Filings by Year

2025 · 2024

Recent SEC Filings (44)

Spruce Biosciences, Inc. SEC Filing History
DateFormDescriptionRisk
Dec 15, 20258-KSpruce Biosciences Relocates HQ, Hints at Officer Changesmedium
Dec 12, 20258-KSpruce Biosciences Announces Board and Executive Changesmedium
Nov 10, 20258-K8-K Filing
Oct 17, 20258-KSpruce Biosciences Announces Board and Compensation Changesmedium
Oct 8, 20258-KSpruce Biosciences Files 8-Kmedium
Aug 14, 202510-QSpruce Biosciences Faces Delisting, Cash Crunch Amid 55% Workforce Cuthigh
Jul 24, 20258-KSpruce Biosciences Files 8-K on Security Holder Mattersmedium
Jun 12, 20258-KSpruce Biosciences Faces Delisting Concernshigh
Jun 6, 2025DEFA14ASpruce Biosciences Files Proxy Supplement for June 9th Meetinglow
May 29, 20258-KSpruce Biosciences Files 8-K with Key Corporate Updatesmedium
May 6, 202510-QSpruce Biosciences Q1 2025 10-Q Filedmedium
Apr 28, 2025DEF 14ASpruce Biosciences Files Definitive Proxy Statementlow
Apr 25, 20258-KSpruce Biosciences Files 8-K on Delisting and Exit Costshigh
Apr 15, 202510-KSpruce Biosciences Files 2024 10-Kmedium
Apr 1, 20258-KSpruce Biosciences Files 8-K on Financialslow
Dec 27, 20248-KSpruce Biosciences Relocates Principal Executive Officeslow
Dec 10, 20248-KSpruce Biosciences Files Routine 8-Klow
Nov 14, 2024SC 13G/ASC 13G/A Filing
Nov 14, 2024SC 13G/ASC 13G/A Filing
Nov 12, 202410-QSpruce Biosciences Files Q3 2024 10-Qmedium

Risk Profile

Risk Assessment: Of SPRB's 32 recent filings, 5 were flagged as high-risk, 19 as medium-risk, and 8 as low-risk. The overall risk profile suggests moderate risk with a balanced mix of positive and cautionary disclosures.

Financial Highlights

Spruce Biosciences, Inc. Financial Summary (10-Q, Aug 14, 2025)
MetricValue
Revenue$0
Net Income-$16.1M
EPSN/A
Debt-to-EquityN/A
Cash Position$16.387M
Operating MarginN/A
Total AssetsN/A
Total DebtN/A

Key Executives

  • Barbara Fiorini
  • B. Shayne Kennedy, Esq.
  • B. Shayne Kennedy

Industry Context

Spruce Biosciences operates in the biotechnology sector, focusing on developing therapies for rare diseases. This industry is characterized by high R&D costs, long development timelines, significant regulatory hurdles, and intense competition for funding and market share. Companies often rely on partnerships and external financing to advance their pipelines.

Top Tags

corporate-governance (5) · delisting (4) · 10-Q (4) · regulatory-filing (4) · amendment (4) · schedule-13d (4) · listing-standards (3) · regulatory (3) · financials (3) · biotech (3)

Key Numbers

Spruce Biosciences, Inc. Key Metrics
MetricValueContext
Date of Report2025-12-11Earliest event reported
SEC File Number001-39594Spruce Biosciences' SEC filing number
Net Loss$16.1Mfor the six months ended June 30, 2025, indicating continued unprofitability
Cash Used in Operations$21.6Mfor the six months ended June 30, 2025, highlighting significant cash burn
Cash and Cash Equivalents$16.4Mas of June 30, 2025, deemed insufficient to fund operations for 12 months
Accumulated Deficit$266.4Mas of June 30, 2025, reflecting substantial historical losses
Workforce Reduction55%effected on April 21, 2025, to prioritize specific product development
Reverse Stock Split Ratio1-for-75effective August 7, 2025, to address minimum bid price requirements
Collaboration Revenue$0for the six months ended June 30, 2025, down from $3.612 million in 2024
Workforce Reduction Expenses$0.9Mincurred during the three months ended June 30, 2025
Total Current Assets$20.953Mas of June 30, 2025, a significant decrease from $44.206 million at December 31, 2024
Total Current Liabilities$8.060Mas of June 30, 2025, down from $15.246 million at December 31, 2024
IRS Employer Identification No.81-2154263Tax identification number for Spruce Biosciences.
Reporting Period End2025-03-31Financials and fair value measurements are as of this date.
Term Loan Origination2019-09-30Date the term loan with Silicon Valley Bank was established.

Related Companies

SPRU · SVB · SPRC

Frequently Asked Questions

What are the latest SEC filings for Spruce Biosciences, Inc. (SPRB)?

Spruce Biosciences, Inc. has 44 recent SEC filings from Jan 2024 to Dec 2025, including 19 8-K, 8 SC 13G/A, 5 10-Q. Each filing includes an AI-generated plain-English summary.

What is the overall sentiment of SPRB filings?

Across 44 filings, the sentiment breakdown is: 1 bullish, 6 bearish, 37 neutral. The dominant sentiment is neutral.

Where can I find Spruce Biosciences, Inc. SEC filings explained simply?

ReadTheFiling provides AI-powered plain-English summaries of all Spruce Biosciences, Inc. (SPRB) SEC filings, including 10-K annual reports, 10-Q quarterly reports, 8-K current reports, and insider trades.

What are the key financial highlights for Spruce Biosciences, Inc.?

Key financial highlights from Spruce Biosciences, Inc.'s most recent 10-Q include metrics such as revenue, net income, EPS, and debt ratios. Visit the filing detail page for the full breakdown.

What is the investment thesis for SPRB?

The investment thesis for SPRB includes bull, base, and bear case scenarios derived from AI analysis of recent SEC filings.

Who are the key executives at Spruce Biosciences, Inc.?

Key executives identified across Spruce Biosciences, Inc.'s filings include Barbara Fiorini, B. Shayne Kennedy, Esq., B. Shayne Kennedy.

What are the main risk factors for Spruce Biosciences, Inc. stock?

Of SPRB's 32 assessed filings, 5 were flagged high-risk, 19 medium-risk, and 8 low-risk.

What are recent predictions and forward guidance from Spruce Biosciences, Inc.?

Forward guidance and predictions for Spruce Biosciences, Inc. are extracted from SEC filings as they are enriched.

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